Coronavirus Impact is included in Chapter 2. The influence of COVID-19 has been considered in the report. The report contains qualitative and quantitative analysis of the entire industry. The report mainly contains different types, applications, and regional historical data from 2017-2021 and forecast data from 2022-2028. Upfront in the drug discovery process, the company is able to screen for rodent cross-reactive clones, which facilitate preclinical studies on candidates of interest.Īnd together with other proprietary technology licensed from BioWa Inc., which boosts antibody-mediated cell killing properties, arGEN-X can generate differentiated antibody therapeutics.īeing outbred, llamas have no blind spots in their immune systems, meaning that diverse antibodies covering virtually any target epitope can be found – even on highly complex targets.Precious Metal Porcelain Teeth market report explains the definition, types, applications, major countries, and major players of the Precious Metal Porcelain Teeth market. This makes llamas able to mount high affinity antibody responses – often human/mouse cross-reactive – against any therapeutic target.įollowing the creation of large libraries of diverse, target-specific antibodies, arGEN-X applies disease-relevant functional assays that enable selection of unique and differentiated therapeutic candidates. While proteins of therapeutic interest are often conserved between human and transgenic mice, they are highly divergent between human and llama. Tim Van Hauwermeiren, CEO of arGEN-X, told BioPharma-Reporter that the company’s antibody discovery platform, which uses llama antibodies rather than the industry “ gold standard” of transgenic mice.īut the llama antibodies offer several advantages over the inbred, transgenic mice, Van Hauwermeiren told us, because of the diversity of the outbred llamas, universal epitope coverage and how easy it is to generate an immune response with the llama antibodies. The companies are working to create human therapeutic antibodies against complex targets involved in severe and rare genetic diseases. ![]() The undisclosed payment announced Thursday was the first demonstration of in vivo proof of concept for one of the antibody discovery programs. Proof of the platform’s success for arGEN-X has resulted in a milestone payment from rare treatment developer Shire Pharmaceuticals.
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